TMC/1,3-Dioxan-2-one

Trimethylene carbonate (1,3-dioxane-2-one) is an organic compound whose properties can be summarized in five aspects: physical, chemical, biocompatibility and degradability, application fields, and safety and storage. I. Physical Properties: Appearance and properties: White crystals or powder. Density: Approximately 1.2-1.25 g/cm³. Melting point: 45-47℃. Boiling point: 255.2℃. Flash point: 148.6℃. Vapor pressure: 0.0165 mmHg (25℃). II. Chemical Properties: Molecular formula and molecular weight: Chemical formula C₄H₆O₃, molecular weight 102.09. Reactivity: Trimethylene carbonate is a cyclic carbonate with high reactivity and can be used to prepare polytrimethylene carbonate (PTMC) through ring-opening polymerization. Solubility: Specific solubility data may vary depending on conditions, but it is generally soluble in some organic solvents. III. Biocompatibility and Degradability Biocompatibility: Polytrimethylene carbonate (PTMC), prepared by ring-opening polymerization of trimethylene carbonate monomers, is a non-toxic biomedical material with good biocompatibility. Biodegradability: PTMC can gradually degrade into carbon dioxide and water in vivo, and the degradation rate can be controlled by adjusting the molecular weight of the polymer. This biodegradability makes PTMC a promising candidate for applications in the biomedical field. IV. Application Areas Biomedical Materials: PTMC has been widely used in biodegradable ligation devices, controlled drug release, and implantable materials. For example, it can be used as surgical sutures, fracture fixation materials, and drug carriers. Tissue Engineering: PTMC has also been widely used in tissue engineering scaffolds, nerve conduits, and implantable materials. Its good biocompatibility and biodegradability make it an ideal material for tissue engineering. Other Fields: In addition to the biomedical field, trimethylene carbonate can also be used as an intermediate in organic synthesis. V. Safety and Storage Safety: Trimethylene carbonate may pose certain hazards to humans and the environment; protective equipment should be worn when handling it. Storage conditions: Trimethylene carbonate should be stored refrigerated at 2-8℃.